It’s worse at night, when the temperature drops. My knees ache. They really ache. Not the muscular sort of ache, nor the done-too-much-running kind. That deep-inside sort of ache. It feels like my 20something joints have been replaced with those of a very senior citizen. If I sit still for a few minutes, when I start to move again the pain, although by no means unbearable, is enough to make me slow.
My lips are permanently dry. I moisten them with Carmex – very good, even though the ill-advised yellow packaging makes it look like superglue – but the relief is only temporary.
When I wake up, my skin is always dry. Nivea Moisturiser and Garnier Face masks help, but the neck and eyebrows and right cheek keep on drying out.
The dandruff has been plain absurd. A scratch of the head results in an avalanche on the shoulder. On the upside, my hair doesn’t get dirty as there’s no sebum being produced. Nonetheless, I’ve taken extreme measures and shaved my head, leaving a BA Baracus type Mohawk down the middle for posterity’s sake. But soon enough I’ll be totally skin.
My temper is shorter. Not that it’s ever especially long, but it’s shorter than normal. Irritability is rife. My serotonin levels are, apparently, lower than they would normally be.
Whenever I go out and there is sunshine, I have to cover up with some factor 40. I smell like I’m on holiday most the time.
I’ve had one drink in over three months, and that was to celebrate Fulham’s extraordinary escape from Premier League relegation. My liver, I’m told, would pack in if I indulge in any kind of binge drinking.
The appetite comes and goes, mostly it’s fine but often I’m craving fatty crap like chocolate, crisps, and fried food. Apparently, isotretinoin – for this barrage of bodily dysfunction is all his fault – relies on fat. It absorbs itself into fat and then gets to work on fucking your body up (with a side-effect of improving the skin condition).
The thing is, I’m not fat. My body mass index is damn perfect. So perhaps, and I’m no physician, but perhaps the body is saying ‘Eat shit, Eddie. We got these annoying brown pills asking for some grease, so get with it and fill yourself up with some Minstrels, Monster Munch and a chicken pie.’
I had a freaky episode a couple of weeks into February when I woke up in the middle of the night with shivers and sweats, an aching jaw and achy joints. The blood pressure dropped, although not worryingly so, and wouldn’t go back up to normal for a couple of days. But within 12 hours of the shivers and shakes, I was feeling fine again. Not so much 24-hour flu as overnight flu.
In short, it’s still me inside the body, but the body’s been interrupted. It’s not going about its business as normal.
It’ll be back soon, hopefully, with a 7-year skin problem solved. No guarantee on that, though, and progress has been disappointingly slow so far. But when the side-effects are so overwhelming and so plentiful, they become the ‘effect’ and the actual cure takes the sideline.
The best way to rationalize this barmy 6-month episode is to tell myself I am sick and I have to tolerate the treatment to get better. Not that I’m sick sick, but there is a bug living on my face and he’s steadfastly and stubbornly refused to be killed by numerous courses of antibiotics, three courses of homeopathy and a Vitamin A-rich diet of carrots, broccoli and mango.
Three-and-a-half months in, and the skin doesn’t feel much better at all, to be frank. Still over two months to go, so I’ve got to stay optimistic. The summer is nearly here, the temperature ought to improve, and my knees might not hurt so much.
Filed under: Eddie's Med Diary, Science Tagged: | accutane, acne, isotretinoin, medication, roaccutane, seratonin, side effect




Hey there ed. I just searched Roaccutane blog on google and found yours. I’m also on the Roaccutane treatment, and almost the exact time into it as well. When I read your blog, I thought to myself… jeeeeezers this guys is a whossy! But the effects of Roaccutane (I think) depends on you as person, your mind and mainly on the dosage.
I don’t have many complaints about Roaccutane for example the sunscreen throughout the treatment. I use sunscreen everyday, even before I started Roaccutane and I’m going to use it after the treatment – and for the year 2008 wiht all the evidence relating to the advantages towards using sunscreen, shouldn’t everyone wear sunscreen anyways? Roaccutane or not…
I’m not complaining about the dry lips since it is an effect that ALWAYS occurs with the treatment – just using and continually using the correct methods is vital.
If your skin is perhaps verrry dry I reccomend you use a tissue-oil such as Bio-oil. I know this sounds ironic since your are taking Roaccutane to reduce your sebum production, but a tissue-oil is not the same oil and it is very advantageous for your skin – and will increase your skins moisture. Remember also that there is a difference between dry skin(low sebum production) and dehydrated skin(without water). You should try to drink a lot of water. Well not crazy, but ±1.5 liters a day is sufficient. Again, I’m used to drink my daily water so this isn’t a big deal.
What you can also do is to drink Omega 3 supplements – also a very advantageous supplement for your skin even if you’re not on Roaccutane.
My biggest concern with Roaccutane(before I went on treatment) was the muscular/joint pains since I’m a very active person(and the booklet warns that it may affect mostly active person)… but I must admit – I have not experience only single pain related to this warning even though I still swim, jog, gym and all my other activities. But not all people are the same…
My ONLY complaints with Roaccutane(and effects I knew that I was going to get) is the “red flush” in your face. But it will eventually go away when my treatment is finished. It looks like I have a sunburn on some photos! lol
anyways [^_-]
I am seaching for some idea to write in my blog… somehow come to your blog. best of luck. Eugene
Eddie! Why are you on Roaccutane? Your skin was fine when I knew you. Sorry to hear that you’re suffering badly with side effects. I myself was on it last year for 2 months and it cleared my 2 year acne up really well. I guess I was lucky as I just suffered the dry lips & nostrils and a bit of joint ache in the hands. I used to just pile acqueous cream on my face during the day. Stick with it my friend, it will be worth it in the end! This stuff is the only thing that really works. Hope you are well otherwise and enjoying life. Much love x
I have been meaning to post something like this on my webpage and this has given me an idea. Cheers.